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Case Report
 
A rare giant gynecomastia and an abnormal 46XY 15ps+ karyotype in a 15-year-old boy
Manuneethimaran Thiyagarajan1, Pragnya Chigurupati2, Balaji Singh K.3
1MS, Assistant Professor, General Surgery, Sri Ramachandra Medical University Porur, Chennai, India.
2MBBS, Postgraduate, General Surgery, Sri Ramachandra Medical University Porur, Chennai, India.
3Professor and Head of Department, General Surgery, Sri Ramachandra Medical University Porur, Chennai, India.

Article ID: 100002S05MT2014
doi:10.5348/S05-2014-2-CR-2

Address correspondence to:
Dr. Manuneethimaran Thiyagarajan
Assistant professor General Surgery, Sri Ramachandra Medical University Porur
Chennai
India – 600087
Email: maadimaran@yahoo.co.in

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How to cite this article:
Manuneethimaran T, Chigurupati P, Singh BK. A rare giant gynecomastia and an abnormal 46XY 15ps+ karyotype in a 15-year-old boy. Edorium J Surg 2014;3:10–13.


Abstract
Introduction: Gynecomastia is one of the common endocrine disorders in adolescent boys. During puberty, up to 70% of the boys have some breast development. However, in this enlargement, up to 75% of the cases resolve spontaneously within 2 years without any treatment. Rarely surgical management is also required to correct the gynecomastia.
Case Report: A 16-year-old boy presented to us with gynecomastia, with a chromosomal aberration of 15ps+. We proceeded with a subcutaneous mastectomy using an infra areolar incision.
Conclusion: The 46XY karyotype with enlarger satellites of acrocentric chromosome 15ps+, is one of the rare entities. Occurrence of Giant gynecomastia in the presence of this particular chromosomal aberration is also a rare entity. In this paper, we would like to highlight these rare entities and the management of the same.

Keywords: Abnormal karyotype with gynecomastia, Giant gynecomastia, Gynecomastia, Subcutaneous Mastectomy


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Author Contributions
Manuneethimaran Thiyagarajan – Acquisition of data, Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Pragnya Chigurupati – Substantial contributions to conception and design, Revising it critically for important intellectual content, Final approval of the version to be published
Balaji Singh K. – Analysis and interpretation of data, Revising it critically for important intellectual content, Final approval of the version to be published
Guarantor of submission
The corresponding author is the guarantor of submission.
Source of support
None
Conflict of interest
Authors declare no conflict of interest.
Copyright
© 2014 Manuneethimaran Thiyagarajan et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.