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Research Article
Impact of neoadjuvant and adjuvant chemotherapy on postoperative complications after mastectomy with immediate breast reconstruction
1 Department of General Surgery, Zagazig University, Zagazig, Egypt
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Hassan A Saad
Department of General Surgery, Zagazig University, Zagazig,
Egypt
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Article ID: 100040S05HS2019
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Saad HA, El Teliti AM, Arafa AS, Abdelbari A. Impact of neoadjuvant and adjuvant chemotherapy on postoperative complications after mastectomy with immediate breast reconstruction. Edorium J Surg 2019;6:100040S05HS2019.ABSTRACT
Aim: Use of chemotherapy has a big role in cancer breast treatment. This study is done to determine the impact and timing of neoadjuvant and adjuvant chemotherapy on postoperative outcomes after mastectomy with immediate breast reconstruction. This study was done in Zagazig University Hospitals, Egypt.
Methods: Retrospective study including 82 patients underwent mastectomy and immediate breast reconstruction with Intervention Systemic neoadjuvant and adjuvant chemotherapy for breast cancer during the period of study (January 2017 to December 2018), with a postoperative follow-up of two years at Zagazig University Surgical Department.
Results: Nine patients (45%) in the adjuvant chemotherapy developed postoperative infections, compared with seven patients (25%) in the neoadjuvant chemotherapy group and 8 patients (24%) who did not receive any chemotherapy (p = 0.05). Overall, 30% of patients had a complication requiring an unplanned return to the surgical room.
Conclusion: The adjuvant chemotherapy group had high rate of infected wound but there were no differences between groups with respect to unplanned reoperation, donor-site complications, or expander loss.
Keywords: Cancer breast, Chemotherapy, Neoadjuvant, Reconstruction
SUPPORTING INFORMATION
Author Contributions:
Hassan A Saad - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ahmed M El Teliti - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Ahmed Salah Arafa - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Amr Abdelbari - Substantial contributions to conception and design, Acquisition of data, Analysis of data, Interpretation of data, Drafting the article, Revising it critically for important intellectual content, Final approval of the version to be published
Guaranter of SubmissionThe corresponding author is the guarantor of submission.
Source of SupportNone
Consent StatementWritten informed consent was obtained from the patient for publication of this article.
Data AvailabilityAll relevant data are within the paper and its Supporting Information files.
Conflict of InterestAuthors declare no conflict of interest.
Copyright© 2019 Hassan A Saad et al. This article is distributed under the terms of Creative Commons Attribution License which permits unrestricted use, distribution and reproduction in any medium provided the original author(s) and original publisher are properly credited. Please see the copyright policy on the journal website for more information.
